NASHVILLE, TN — Josh and Jacqui Hudson are the husband-wife duo transforming healthcare through their rapidly growing wellness company, Optimize U.

What began as a hormone clinic in 2016 has expanded to 36 locations nationwide in 2025, driven by their passion for holistic health and a desire to address gaps in traditional healthcare.

Many trust Optimize U due to their extensive experience in the healthcare system. Josh, RN, is used to the space of medicine and wellness. “Josh was a nurse who had gotten into medical device sales, and he came home one day saying, ‘I think I want to start a hormone clinic,'” Jacqui said. Within 48 hours, Josh had developed a comprehensive business plan with their main partner, Jerry Smith, a physician assistant. Six months later, they opened their first clinic. Josh’s background in healthcare, working in hospice care and at Western State psychiatric facility in Hopkinsville, Kentucky, exposed him to the limitations of conventional medicine. “He had a lot of background seeing people struggle,” Jacqui explains. “Some of the stories he shared were absolutely unfortunate.”

Jacqui herself grew up with a mother who prioritized natural remedies. “I don’t ever remember her taking Tylenol or ibuprofen. All of our remedies were natural. Olive oil was the cure-all for everything.”

That is when they both knew it was time for them to change patient stories like that.

What sets Optimize U apart is their comprehensive approach to wellness. “We don’t want to be just another hormone therapy clinic,” Jacqui says. “We want to optimize your entire body.” Their services include Hormone optimization, recovery services including compression boots for lymphatic drainage, cold plunge therapy, Cryotherapy, infrared sauna, red light therapy, Vibroacoustic sound bed, and so much more. “Everything that we have is specifically for decreasing inflammation,” Jacqui explains.

“People thought wellness was just for those involved in sports, but we’re trying to bring that into mainstream at affordable prices because we know how important it is to utilize those things frequently.”

Optimize U positions itself between traditional primary care and more expensive functional medicine practices. “We’re trying to find that really good balance,” Jacqui says. She notes that many medical professionals are constrained by the systems they work in: “They’re employed by places that unfortunately put handcuffs on them and they can’t practice how they probably want to.” This has created a movement of providers joining Optimize U who eager to make an impact and change their community’s lives.

The most rewarding aspect of their work is witnessing transformative results.

“I have had friends who were on the verge of divorce,” Jacqui shares. “The number of marriages that we have saved has been amazing. Not just that, but the people that we’ve even helped get pregnant has been even more rewarding.” Hormone Optimization is critical to our mental health and they knew that with just a simple and effective fix, people did not have to live his or her life harder than it needed to be. This is just one of the many ways they are helping people gain back their life, voice, and confidence.

As Optimize U continues to grow, they’re expanding their services at their Nashville flagship headquarters to include DEXA scan machines for bone health assessment. “We don’t just look at the shiny new objects in this space,” Jacqui explains. “We always lead with science.” Despite their busy schedule growing the business, Jacqui and Josh make time to enjoy their lake home on Kentucky Lake, travel, and engage with the Nashville community.

To start your journey with them, visit their website and find a location nearest you.